Olaparib

Quality manufacturer supply Olaparib 763113-22-0 in stock with high standard We provide high quality Olaparib (CAS 763113-22-0), at a very affordable prices to our customers.

1.What is the Olaparib ?

Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.

Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.[Cayman Chemical]

2.What is the CAS number for Olaparib ?

The CAS number of Olaparib is 763113-22-0.

More information of Olaparib 763113-22-0 are:

3.What is the molecular formula of Olaparib ?

The chemical formula of Olaparib is C₂₄H₂₃FN₄O₃ which containing 24 Carbon atoms,23 Hydrogen atoms,1 Fluorine atoms,4 Nitrogen atoms and 3 Oxygen atoms,and the molecular weight, and the molecular weight of Olaparib is 434.47

4.What is Olaparib(763113-22-0)used for?

Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM, respectively) but is less effective against the PARP tankyrase-1 (IC50 = 1.5 μM). It can be used in cells and in animals, alone or in combination therapy with alkylating agents, to block BER and increase cancer cell death.

InChI:InChI=1/C24H23FN4O3/c25-20-8-5-15(14-21-17-3-1-2-4-18(17)22(30)27-26-21)13-19(20)24(32)29-11-9-28(10-12-29)23(31)16-6-7-16/h1-5,8,13,16H,6-7,9-12,14H2,(H,27,30)

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5.Quality manufacturer supply Olaparib 763113-22-0 in stock with high standard

SHUNYUANSHENG BIO-PHARMTECH CO., LTD is a quality supplier of Olaparib. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Olaparib 763113-22-0.