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(E)-4-(2-methoxynaphthalen-6-yl)but-3-en-2-one

Detailed Information

  • Product Name:(E)-4-(2-methoxynaphthalen-6-yl)but-3-en-2-one
  • CasNo.:127053-22-9
  • MF:C15H14O2
  • MW:226.275

pd_nature

  • Purity:99%
  • pd_boiling:120-121℃ (ethanol )
  • Packing:
  • Throughput:

Product Details;

CasNo: 127053-22-9

MF: C15H14O2

Top Quality Chinese Manufacturer supply 127053-22-9 (E)-4-(2-methoxynaphthalen-6-yl)but-3-en-2-one

  • Molecular Formula:C15H14O2
  • Molecular Weight:226.275
  • Melting Point:120-121℃ (ethanol ) 
  • Boiling Point:406.2±20.0 °C(Predicted) 
  • PSA:26.30000 
  • Density:1.119±0.06 g/cm3(Predicted) 
  • LogP:3.45060 

127053-22-9 Relevant articles

Carbon-Carbon bond cleavage in activation of the prodrug nabumetone

Varfaj, Fatbardha,Zulkifli, Siti N. A.,Park, Hyoung-Goo,Challinor, Victoria L.,De Voss, James J.,De Montellano, Paul R. Ortiz

, p. 828 - 838 (2014)

Carbon-carbon bond cleavage reactions ar...

Process research and structural studies on nabumetone

Prabhakar,Reddy, C. Bakki,Reddy, Ch. Maheedhara,Nageshwar,Devi, A. Sivalakshmi,Babu, J. Moses,Vyas,Sarma,Reddy

, p. 121 - 125 (1999)

A short, simple and economical process f...

An efficient benchtop system for multigram-scale kinetic resolutions using aldolase antibodies

Turner, James M.,Bui, Tommy,Lerner, Richard A.,Barbas III, Carlos F.,List, Benjamin

, p. 2772 - 2774 (2000)

The preparative scale kinetic resolution...

Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose-6-phosphate Aldolase

Roldán, Raquel,Sanchez-Moreno, Israel,Scheidt, Thomas,Hélaine, Virgil,Lemaire, Marielle,Parella, Teodor,Clapés, Pere,Fessner, Wolf-Dieter,Guérard-Hélaine, Christine

, p. 5005 - 5009 (2017)

d-Fructose-6-phosphate aldolase (FSA) wa...

Organocatalytic diastereo- And enantioselective oxa-hetero-Diels-Alder reactions of enones with aryl trifluoromethyl ketones for the synthesis of trifluoromethyl-substituted tetrahydropyrans

Pasha, Maira,Tanaka, Fujie

supporting information, p. 9242 - 9250 (2021/11/16)

Tetrahydropyran derivatives are found in...

A CATALYST FOR ONE POT SYNTHESIS OF NABUMETONE AND PROCESS OF PREPARATION THEREOF

-

Page/Page column 2; 13-17, (2020/11/30)

The present invention relates to novel h...

Enantiocomplementary synthesis of γ-nitroketones using designed and evolved carboligases

Garrabou, Xavier,Verez, Rebecca,Hilvert, Donald

supporting information, p. 103 - 106 (2017/05/16)

Artificial enzymes created by computatio...

127053-22-9 Process route

rac-4-Hydroxy-4-(6-methoxynaphthalen-2-yl)pentan-2-one

rac-4-Hydroxy-4-(6-methoxynaphthalen-2-yl)pentan-2-one

4-(6'-methoxy-2'-naphthyl)-3-buten-2-one
127053-22-9

4-(6'-methoxy-2'-naphthyl)-3-buten-2-one

acetone
67-64-1

acetone

(R)-4-Hydroxy-4-(6-methoxynaphthalen-2-yl)pentan-2-one

(R)-4-Hydroxy-4-(6-methoxynaphthalen-2-yl)pentan-2-one

Conditions
Conditions Yield
With phosphate buffered saline; aldolase antibodies 38C2; In toluene; for 193h;
44%
6-methoxynaphthalene-2-carbaldehyde
3453-33-6

6-methoxynaphthalene-2-carbaldehyde

acetone
67-64-1

acetone

4-(6'-methoxy-2'-naphthyl)-3-buten-2-one
127053-22-9

4-(6'-methoxy-2'-naphthyl)-3-buten-2-one

Conditions
Conditions Yield
With sodium hydroxide; In water; at 20 ℃;
51%
With potassium hydroxide; In methanol; water; for 2h; Reflux;
46%
With morpholin-4-ium 2,2,2-trifluoroacetate; at 75 ℃;
With retro-aldolase "RA95.5-8F; sodium chloride; In aq. buffer; at 29 ℃; for 48h; pH=7.5; Enzymatic reaction;

127053-22-9 Upstream products

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    6-methoxynaphthalene-2-carbaldehyde

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    acetone

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    5111-65-9

    2-Bromo-6-methoxynaphthalene

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    78-94-4

    methyl vinyl ketone

127053-22-9 Downstream products

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    42924-53-8

    nabumetone

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    1258422-88-6

    (1S,6R)-1'-benzyl-6-(6-methoxynaphthalen-2-yl)-2-methylspiro[cyclohex[2]ene-1,3'-indoline]-2',4-dione

  • 65726-31-0
    65726-31-0

    3,4,5-Trimethoxy-benzoic acid 3-(6-methoxy-naphthalen-2-yl)-1-methyl-propyl ester

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