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6-amino-3-cyclopropyl-1-(2-fluoro-4-iodophenyl)pyrimidine-2,4(1H,3H)-dione

Detailed Information

  • Product Name:6-amino-3-cyclopropyl-1-(2-fluoro-4-iodophenyl)pyrimidine-2,4(1H,3H)-dione
  • CasNo.:871700-28-6
  • MF:C13H11FIN3O2
  • MW:387.152

pd_nature

  • Purity:99%
  • pd_boiling:
  • Packing:
  • Throughput:

Product Details;

CasNo： 871700-28-6

MF： C13H11FIN3O2

Quality manufacturer supply 6-amino-3-cyclopropyl-1-(2-fluoro-4-iodophenyl)pyrimidine-2,4(1H,3H)-dione 871700-28-6 in stock with high standard

  • Molecular Formula:C13H11FIN3O2
  • Molecular Weight:387.152
  • Boiling Point:449.1±55.0 °C(Predicted) 
  • PKA:4.09±0.70(Predicted) 
  • PSA：70.02000 
  • Density:1.957±0.06 g/cm3(Predicted) 
  • LogP:2.24120 

871700-28-6 Relevant articles

Synthesis of novel coumarinyl-pyrido[2,3-d]pyrimidine-2,4-diones using task-specific magnetic ionic liquid, [AcMIm]FeCl4 as catalyst

Ambati, Srinivasa Rao,Patel, Jeevan Lal,Gudala, Satish,Chandrakar, Komal,Penta, Santhosh,Mahapatra,Banerjee, Subhash

, p. 104 - 111 (2020)

An acid-functionalized magnetic ionic li...

Method for synthesizing key intermediate of trametinib

-

Paragraph 0029, (2019/02/27)

The invention discloses a method for syn...

5-AMINO-2,4,7-TRIOXO-3,4,7,8-TETRAHYDRO-2H-PYRIDO’2,3-D! PYRIMIDINE DERIVATIVES AND RELATED COMPOUNDS FOR THE TREATMENT OF CANCER

-

Page/Page column 151, (2008/06/13)

The present invention relates to a pyrim...

871700-28-6 Process route

1-(2-cyanoacetyl)-1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea
871700-26-4

1-(2-cyanoacetyl)-1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea

6-amino-3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-1H-pyrimidine-2,4-dione
871700-28-6

6-amino-3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-1H-pyrimidine-2,4-dione

Conditions
Conditions Yield
With sodium hydroxide; In water; at 80 - 90 ℃;
94%
With sodium hydroxide;
88%
With sodium hydroxide; In water; at 80 ℃; for 1h;
6-amino-3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-1H-pyrimidine-2,4-dione
871700-28-6

6-amino-3-cyclopropyl-1-(2-fluoro-4-iodo-phenyl)-1H-pyrimidine-2,4-dione

3-chloro-3-(2-oxo-2H-chromen-3-yl)acrylaldehyde

3-chloro-3-(2-oxo-2H-chromen-3-yl)acrylaldehyde

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-(2-oxo-2H-chromen-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-(2-oxo-2H-chromen-3-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-dione

Conditions
Conditions Yield
With 1-carboxymethyl-3-methylimidazolium tetrachloroferrate; at 60 ℃; Reagent/catalyst; Temperature;
94%

871700-28-6 Upstream products

  • 871700-26-4
    871700-26-4

    1-(2-cyanoacetyl)-1-cyclopropyl-3-(2-fluoro-4-iodophenyl)urea

871700-28-6 Downstream products

  • 871700-30-0
    871700-30-0

    N'-[1-cyclopropyl-3-(2-fluoro-4-iodo-phenyl)-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-4-yl]-N,N-dimethyl-formamidine

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