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CasNo: 1300750-79-1
A general and efficient procedure for th...
4-amino-3-chloropyridine
4-amino-3-chloro-5-iodopyridine
Conditions | Yield |
---|---|
With
iodine; sodium carbonate; potassium iodide;
In
water;
for 120h;
Inert atmosphere;
Reflux;
|
49% |
4-amino-3-chloro-5-iodopyridine
7-chloro-2,3-diphenyl-1H-pyrrolo[3,2-c]pyridine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.08 h / Inert atmosphere
1.2: 20 °C / Inert atmosphere
1.3: 0.5 h / Inert atmosphere
2.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; lithium bromide / N,N-dimethyl-formamide / 48 h / 100 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; sodium hydride; sodium carbonate; lithium bromide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
2.1: Larock heteroannulation;
|
|
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.08 h / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; lithium bromide / N,N-dimethyl-formamide / 48 h / 100 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; sodium hydride; sodium carbonate; lithium bromide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
2.1: Larock heteroannulation;
|
|
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 20 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; lithium bromide / N,N-dimethyl-formamide / 48 h / 100 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; sodium hydride; sodium carbonate; lithium bromide;
In
tetrahydrofuran; N,N-dimethyl-formamide;
|
4-amino-3-chloropyridine
7-chloro-2,3-diphenyl-1H-pyrrolo[3,2-c]pyridine