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3-Chloro-5-iodopyridin-4-amine

Detailed Information

  • Product Name:3-Chloro-5-iodopyridin-4-amine
  • CasNo.:1300750-79-1
  • MF:
  • MW:254.458

pd_nature

  • Purity:99%
  • pd_boiling:
  • Packing:
  • Throughput:

Product Details;

CasNo: 1300750-79-1

Factory sells 3-Chloro-5-iodopyridin-4-amine 1300750-79-1 with sufficient production capacity

  • Molecular Formula:C5H4ClIN2
  • Molecular Weight:254.458

1300750-79-1 Relevant articles

Palladium-catalyzed synthesis of 2,3-disubstituted 5-azaindoles via heteroannulation reaction and of 2-substituted 5-azaindoles through domino sila-Sonogashira/5-endo cyclization

Livecchi, Marion,Calvet, Geraldine,Schmidt, Frederic

experimental part, p. 5006 - 5016 (2012/07/03)

A general and efficient procedure for th...

1300750-79-1 Process route

4-amino-3-chloropyridine
19798-77-7

4-amino-3-chloropyridine

4-amino-3-chloro-5-iodopyridine
1300750-79-1

4-amino-3-chloro-5-iodopyridine

Conditions
Conditions Yield
With iodine; sodium carbonate; potassium iodide; In water; for 120h; Inert atmosphere; Reflux;
49%
4-amino-3-chloro-5-iodopyridine
1300750-79-1

4-amino-3-chloro-5-iodopyridine

7-chloro-2,3-diphenyl-1H-pyrrolo[3,2-c]pyridine
1300750-89-3

7-chloro-2,3-diphenyl-1H-pyrrolo[3,2-c]pyridine

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.08 h / Inert atmosphere
1.2: 20 °C / Inert atmosphere
1.3: 0.5 h / Inert atmosphere
2.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; lithium bromide / N,N-dimethyl-formamide / 48 h / 100 °C / Inert atmosphere
With bis-triphenylphosphine-palladium(II) chloride; sodium hydride; sodium carbonate; lithium bromide; In tetrahydrofuran; N,N-dimethyl-formamide; 2.1: Larock heteroannulation;
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.08 h / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; lithium bromide / N,N-dimethyl-formamide / 48 h / 100 °C / Inert atmosphere
With bis-triphenylphosphine-palladium(II) chloride; sodium hydride; sodium carbonate; lithium bromide; In tetrahydrofuran; N,N-dimethyl-formamide; 2.1: Larock heteroannulation;
Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 20 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; lithium bromide / N,N-dimethyl-formamide / 48 h / 100 °C / Inert atmosphere
With bis-triphenylphosphine-palladium(II) chloride; sodium hydride; sodium carbonate; lithium bromide; In tetrahydrofuran; N,N-dimethyl-formamide;

1300750-79-1 Upstream products

  • 19798-77-7
    19798-77-7

    4-amino-3-chloropyridine

1300750-79-1 Downstream products

  • 1300750-89-3
    1300750-89-3

    7-chloro-2,3-diphenyl-1H-pyrrolo[3,2-c]pyridine

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