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tert-butyl 6-(bromomethyl)pyridin-2-ylcarbamate

Detailed Information

  • Product Name:tert-butyl 6-(bromomethyl)pyridin-2-ylcarbamate
  • CasNo.:400781-16-0
  • MF:C11H15BrN2O2
  • MW:287.15300

pd_nature

  • Purity:99%
  • pd_boiling:
  • Packing:
  • Throughput:

Product Details;

CasNo： 400781-16-0

MF： C11H15BrN2O2

Chinese Factory Supply Wholesale tert-butyl 6-(bromomethyl)pyridin-2-ylcarbamate 400781-16-0 with Cheap Price

  • Molecular Formula:C11H15BrN2O2
  • Molecular Weight:287.15300
  • Boiling Point:315.6±32.0 °C(Predicted) 
  • PKA:12.27±0.70(Predicted) 
  • PSA：54.71000 
  • Density:1.427±0.06 g/cm3(Predicted) 
  • LogP:3.33710 

400781-16-0 Relevant articles

ARYL AND HETEROARYL-CARBOXAMIDE SUBSTITUTED HETEROARYL COMPOUNDS AS TYK2 INHIBITORS

-

Page/Page column 106, (2021/10/15)

Novel carboxamide substituted compounds ...

Phenyl oxime derivative and preparation method and application thereof

-

Paragraph 0115-0117, (2020/12/31)

The invention relates to a phenyl oxime ...

An affinity reagent for the recognition of pyrophosphorylated peptides

Conway, John H.,Fiedler, Dorothea

supporting information, p. 3941 - 3945 (2015/03/30)

A resin-bound dinuclear zinc(II) complex...

400781-16-0 Process route

tert-butyl 6-(hydroxymethyl)-2-pyridinylcarbamate
203321-83-9

tert-butyl 6-(hydroxymethyl)-2-pyridinylcarbamate

tert-butyl (6-(bromomethyl)pyridin-2-yl)carbamate
400781-16-0

tert-butyl (6-(bromomethyl)pyridin-2-yl)carbamate

Conditions
Conditions Yield
With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 ℃; for 3h;
89%
With carbon tetrabromide; potassium carbonate; triphenylphosphine; In dichloromethane; at 0 - 20 ℃;
29%
2-(tert-butoxycarbonylamino)-6-picoline
90101-22-7

2-(tert-butoxycarbonylamino)-6-picoline

tert-butyl (6-(bromomethyl)pyridin-2-yl)carbamate
400781-16-0

tert-butyl (6-(bromomethyl)pyridin-2-yl)carbamate

Conditions
Conditions Yield
With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; at 77 ℃;
25%

400781-16-0 Upstream products

  • 4248-19-5
    4248-19-5

    tert-butyl carbazate

  • 34160-40-2
    34160-40-2

    6-bromo-2-pyridinecarbaldehyde

  • 203321-83-9
    203321-83-9

    tert-butyl 6-(hydroxymethyl)-2-pyridinylcarbamate

  • 36052-26-3
    36052-26-3

    methyl 6-aminopyridine-2-carboxylate

400781-16-0 Downstream products

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    1438409-82-5

    (Z)-3-((6-aminopyridin-2-yl)methyl)-5-(4-ethoxybenzylidene)thiazolidine-2,4-dione

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